Rapid vaccine development against deadly diseases
Scientists from the Uniformed Services University of the Health Sciences (USU) have developed a new preparation method that renders a virus or bacterium non-infectious while preserving its...
View ArticleMultitarget paradigm in drug discovery
Increasing evidence that several drug compounds exert their effects through interactions with multiple targets is boosting the development of research fields that challenge the data reductionism...
View ArticleTwo-Layer Screen Locates Both Drugs and Targets
Scripps researchers are exploring a new screening method that combines a phenotype-based screen for compounds with a desired cellular effect, and a target-based screen to determine which molecular...
View ArticleHuman, animal or plant mixed in new R&D recipe
Can a crop science team of ag-bio investigators provide some real insights that could help advance new drugs for humans and animals? Bayer believes so, and one of its top researchers says you can...
View ArticleCancer Research UK will repurpose an AstraZeneca asthma drug for kidney cancer
Cancer Research UK has struck a deal with AstraZeneca ($AZN) to repurpose an experimental therapy originally developed by the drug giant for asthma and study its ability to fight kidney cancer. Under...
View ArticleStomaching stress
CAMBRIDGE, Mass.—Scientists at the Massachusetts Institute of Technology have discovered that ghrelin, known as the “hunger hormone,” plays a pivotal role in the widespread issue of posttraumatic...
View ArticlePotential drug targets for early onset glaucoma
Using a novel high-throughput screening process, scientists have for the first time identified molecules with the potential to block the accumulation of a toxic eye protein that can lead to early onset...
View ArticleADC SUMMIT 19TH & 20TH MAY 2014
Venue: Holiday Inn Regents Park Hotel, London, United Kingdom Antibody Drug Conjugates (ADCs) offer the promise and potential of delivering powerful tumour-killing activity with the advantage of...
View ArticlePain Therapeutics 19TH & 20TH MAY 2014
Venue: Holiday Inn Regents Park Hotel, London, United Kingdom SMi are proud to present their 14th Annual Pain Therapeutics Conference taking place in Central London on Monday 19th and Tuesday 20th May...
View ArticleToward Drug Repurposing in Epigenetics
DNA hypomethylating drugs that act on DNA methyltransferase (DNMT) isoforms are promising anticancer agents. By using a well-characterized live-cell system to measure DNA methylation revisions...
View ArticleMechanism that boosts bone growth
A newly discovered mechanism that promotes bone growth could lead to novel treatments for osteoporosis, which affects an estimated one in three women and one in 12 men in the U.S. Overall, about 55% of...
View ArticleAntiviral drug could treat H7N9 flu
Novavax ($NVAX) and Novartis ($NVS) have both been racing to bring to market a vaccine for the avian H7N9 flu, which has caused more than 130 infections and 43 deaths in China. But in the absence of an...
View ArticleUK “breakthrough” drug program
Impressed by the success of the FDA’s breakthrough therapy designation, U.K. regulators are considering a similar effort to speed the path for promising drugs, according to an industry group. The...
View ArticleAntipsychotic drugs use to treat brain tumors
Researchers are finding more potential uses for existing drugs by repurposing them to treat other medical conditions. One class of FDA-approved antipsychotic drugs may provide a new approach to...
View ArticleBig Pharma superteam joins NIH to share data
The National Institutes of Health has persuaded 10 rival drugmakers to briefly set aside their competitive spirits and collaborate on drug discovery projects in four major diseases, pooling their data...
View ArticleEpilepsy drug reverses fatty liver disease
A commonly used epilepsy drug may be able to stop fatty liver disease and prevent Type 2 diabetes in obese people, according to a new study by Johns Hopkins researchers. Scientists found that valproic...
View ArticleB-cells aggravate autoimmune diseases
Scientists in Freiburg may have discovered a fundamental aggravating factor in autoimmune diseases. If B-lymphocytes lack the protein PTP1B, the cells will become hyperactive for stimulatory signals...
View ArticleAdaptor protein role in diabetes, cancer treatments
A protein known to be part of a complex communications network within the cell has also been found to be associated with important processes involved in cancer and diabetes. In a study that will be...
View ArticleStroke drug shows promise for people with Lou Gehrig’s disease
Keck School of Medicine of USC neuroscientists have unlocked a piece of the puzzle in the fight against Lou Gehrig’s disease, a debilitating neurological disorder that robs people of their motor...
View ArticleUCSF, Stanford and Johns Hopkins join FDA partnership to speed drug development
At a time when Big Pharma is increasingly tapping academic institutions for expertise in informatics and data-driven computer models for drug discovery, the FDA has selected Johns Hopkins University,...
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